MyBioSource.com's Mouse Mapk14 Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The Mouse Mapk14 Antibody (N-term) was generated using CRK1, Hog, MAPK14, mitogen-activated protein kinase 14, p38 alpha, p38 MAP kinase, and p38 MAPK as the antigen and it reacts with Human, and Mouse.
Description
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression